ReFoam™ is an innovative foam scaffold for treating periodontal disease and filling bone defects

ReFoam™ is a biocompatible and biodegradable scaffold designed for filling and reconstructing bone defects in the maxillofacial complex.
It features a three-dimensional foam scaffold that supports tissue repair and recovery.
With an eye to the dental clinician’s needs, we are developing a versatile product line to support the various clinical indications.

Launching 2026
Tutorials
tissue

CellFoam™.Inside.

CellFoam™ technology is a protein-based foam scaffold designed to support the body’s natural tissue healing process. It helps the body do what it does best, to heal. When applied into damaged tissue, CellFoam™ promotes natural tissue repair and effectively helps repair anatomical defects. The scaffold naturally degrades in about 3-5 months, while a new healthy tissue takes place.

It's easy to use ReGum™Vet: only 4 simple steps

Step 1

Soak ReGum™ Vet   

to reconstitute elasticity

Step 2

Trim ReGum™ Vet

to fit surgical site

Step 3

Place ReGum™ Vet

in the surgical site

Step 2

 Close the surgical site

Nothing motivates us more than seeing real results

Don't take our word for it, see what clinicians have to say

❝ We optimized this innovative product to best serve our canine patients and colleague veterinarians. Also, with our clinical research team we later scientifically proved that the addition of the ReGum™ is superior to standard open periodontal therapy alone in periodontal tissue repair in dogs with naturally occurring periodontitis.❞
Dr. Ana NemecDVM, PhD, Dipl. AVDC, Dipl. EVDC, Assist. prof. Primary investigator of the clinical study.
Dr. Ana Nemec
❝ There was no way to elevate the bone line when the furcation is there. ReGum™ Vet is the first potential therapy to restore bone line. Many practices assume that having dental radiography will lead to saving more teeth, but often it results in discovering more disease and extracting more teeth. This is where ReGum™ Vet makes a difference – it enables us to preserve more teeth than we could before.❞
Dr. Jen MathisDAVDC Board Certified-Veterinary Dentist and Oral Surgeon
Dr. Jen Mathis
❝ In surgeries with high risk of bleeding, I feel more comfortable with vitaloc™ by my side vitaloc™ has demonstrated to be very effective in bleeding control, more than many other hemostatic products I have used From my experience, vitaloc™ is very easy and safe to use. ❞
Dr. Jerzy GaworDVM, PhD, Dipl AVDC, Dipl EVDC, Fellow AVD
Dr. Jerzy Gawor

ReFoam™ Benefits

ReFoam™ provides a comprehensive solution for the treatment of periodontitis, a condition that affects 40%-70% of adults. This advanced foam scaffold supports tissue growth, including bone and soft tissue, through a single procedure. Unlike existing market options, it effectively addresses all layers impacted by the disease.

 

 

Key advantages

  • Enables significant vertical and horizontal bone recovery
  • Stimulates recovery of both bone and soft tissue synchronously
  • Eliminates the need for additional GTR membranes
  • Reduces the need for repeated future procedures
  • Biodegradable & biocompatible.
  • Safe
  • Easy to use

FAQ

ReFoam™ is an innovative foam-based scaffold designed for the repair of bony defects and repair of damaged dental tissues in humans. It is based on BioChange’s proprietary CellFoam™ technology.

ReFoam™ is being developed to treat periodontal disease, a widespread condition affecting 40–70% of adults over 30. It aims to restore bone and soft tissues, including functional and structural, offering a comprehensive tissue repair solution.

 

Not yet. ReFoam™ is currently undergoing regulatory review, the clearance for human dental use is expected by mid-2026.

A veterinary version of the product has already been successfully launched, demonstrating strong clinical and commercial results with over 40k unit deployed (as of mis 2025). This serves as a robust proof of safety and efficacy and supports the ongoing development of the human version.

ReFoam™ will be launched in multiple sizes to accommodate various clinical needs. Specific configurations will be announced closer to the official launch.

The expected launch date is mid-2026, pending regulatory clearance.

Visit www.biochange.life for the latest updates, or contact our team directly at info@biochange.life

We are always looking for new business opportunities, for more info, please contact :Hilit Hochman, VP Sales& Marketing at BioChange: hilit@BioChange.life

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